Issue 23, 2006

Efficient Friedel–Crafts alkylation of indoles and pyrrole with enones and nitroalkene in water

Abstract

An operationally simple and entirely green protocol for heteropoly acid (10 mg) catalyst conjugate addition of indoles and pyrrole to unsaturated carbonyl compounds and nitroalkene in water at ambient temperature in good to excellent yields has been developed.

Graphical abstract: Efficient Friedel–Crafts alkylation of indoles and pyrrole with enones and nitroalkene in water

Supplementary files

Article information

Article type
Communication
Submitted
18 Jul 2006
Accepted
06 Oct 2006
First published
17 Oct 2006

Org. Biomol. Chem., 2006,4, 4275-4277

Efficient Friedel–Crafts alkylation of indoles and pyrrole with enones and nitroalkene in water

N. Azizi, F. Arynasab and M. R. Saidi, Org. Biomol. Chem., 2006, 4, 4275 DOI: 10.1039/B610263H

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